Charalambos Charalambous
General Surgeon
“Complex surgery requires more than technical skill; it requires judgment, preparation, and a relentless commitment to the patient.”
Dr. Charalambos Charalambous is a General Surgeon with specialized expertise in Surgical Oncology and in the surgical management of gastrointestinal malignancies.
His clinical practice focuses on the diagnosis and surgical treatment of complex abdominal conditions, as well as the management of oncologic diseases of the stomach, colon, liver, pancreas, and biliary tract. In parallel, he provides comprehensive care for a wide spectrum of benign surgical conditions, including hernia repair (inguinal, ventral, and incisional), gallbladder disease (laparoscopic cholecystectomy), and other common general surgical diseases.
His approach is grounded in the principles of evidence-based medicine, personalized patient care, and close collaboration within multidisciplinary medical teams, aiming to achieve the best possible outcomes in both complex oncologic and routine surgical cases.
He completed his General Surgery training at Nicosia General Hospital, one of Cyprus’ major tertiary referral centers, where he served as Chief Resident. He subsequently obtained a ChM (Master of Surgery) with Distinction from the University of Edinburgh and further advanced his surgical training through a short clinical fellowship in Manchester, United Kingdom.
Dr. Charalambous has extensive experience in advanced oncologic and complex abdominal surgery, working within multidisciplinary teams to deliver comprehensive and individualized cancer care.
His clinical interests include colorectal cancer surgery, liver and pancreatic surgery, retroperitoneal sarcomas, as well as benign general surgical conditions such as abdominal wall hernias, gallbladder disease, and minimally invasive procedures, with a strong commitment to evidence-based practice, surgical precision, and optimal patient outcomes.
Education & Academic Experience
2012 - 2013 - Internship in Internal Medicine and General Surgery, Nicosia General Hospital, Cyprus
2014 - 2020 - Residency in General Surgery, Nicosia General Hospital, Cyprus
2019 - Clinical Fellow in Colorectal Surgery, Manchester Royal Infirmary, United Kingdom
Professional Experience
2020 – 2026 General Surgeon Department of Surgical Oncology & HPB Surgery Mediterranean Hospital of Cyprus
2026 – Present General Surgeon, German Medical Institute (GMI), Cyprus
Certifications & Courses
2013 - Advanced Trauma Life Support (ATLS), Nicosia, Cyprus
2024 - Certified PIPAC Training Course (Pressurized Intraperitoneal Aerosol Chemotherapy), Paris University Hospital, Paris, France. Hands-on training in technique, indications, and perioperative management
Scientific Publications
1.Parpounas C, Morris D, Bramis K, Papalambros A, Lazarou V, Charalambous C, Petrou A. Total pericystectomy in liver echynococcal cysts using bipolar sealing coupled with saline device. J Liver Res Disord Ther. 2017;3(6):155‒157. DOI: 10.15406/jlrdt.2017.03.00077
2.Lazarou, V., Petrou, A., Charalambous, C., & Astras, G. (2019). First-Line FOLFIRINOX chemotherapy in initially unresectable locally advanced pancreatic cancer: Retrospective clinical data analysis from a single HPB center. European Journal of Surgical Oncology, 45(2), E68.
3. Lazarou, V., Dervenis, D., Charalambous, C., & Petrou, A. (2019). Associating liver partition and portal vein ligation for staged hepatectomy offers high oncological feasibility with adequate patient safety: A prospective study at a single center. European Journal of Surgical Oncology, 45(2), E68.
4.Petrou, Lazarou, Charalambous, Astras, & Dervenis. (2019). Retrospective study analysis of the safety and feasibility rates of in patients treated with Nanoknife for locally advanced pancreatic cancer. European Journal of Surgical Oncology, 45(2), E73.
5.Lazarou, Dervenis, Astras, Charalampous, & Petrou. (2019). Irreversible electroporation (Nanoknife) of unresectable pancreatic cancer: Effectiveness and safety - Single Center Experience/Analysis. European Journal of Surgical Oncology, 45(2), E66.
6.Lazarou, Dervenis, Charalambous, & Petrou. (2019). Associating liver partition and portal vein ligation for staged hepatectomy offers high oncological feasibility with adequate patient safety: A prospective study at a single center. European Journal of Surgical Oncology, 45(2), E68.
7.Petrou, Lazarou, Charalambous, Astras, & Dervenis. (2019). Retrospective study analysis of the safety and feasibility rates of in patients treated with Nanoknife for locally advanced pancreatic cancer. European Journal of Surgical Oncology, 45(2), E73.
8.Charalambous P, Moris D, Karachaliou GS, Papalampros A, Dimitrokallis N, Tsilimigras DI, Oikonomou D, Petrou A. The efficacy and safety of the open approach irreversible electroporation in the treatment of pancreatic cancer: A systematic review. Eur J Surg Oncol. 2020 Sep;46(9):1565-1572. doi: 10.1016/j.ejso.2020.05.017. Epub 2020 May 30. PMID: 32536525.
9.Kastoris, A. C., Fragkiadakis, G., Michaelides, M., Charalambous, C., Petrou, A., & Kyprianou, T. (2017). Postoperative intensive care course of patients undergoing first and second stage of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS). Intensive Care Medicine Experimental, 5(Suppl 2), 0363.
Academic Activity
• Buschke-Lowenstein Tumour: Malignant transformation of a giant perianal condyloma (Case Report) - 12th Greek Cypriot Surgical Conference, Nicosia, Cyprus, 12-13 December 2015
• Retroperitoneal Sarcomas: Ten years of experience - 12th Greek Cypriot Surgical Conference, Nicosia, Cyprus, 12-13 December 2015
• Irreversible Electroporation (Nanoknife) of Unresectable Pancreatic Cancer: Effectiveness and Safety – A Two-Centre Experience. 31st Panhellenic Surgical Conference & Surgical Forum, Athens, Greece, 21-24 of November 2018
• Comprehensive Surgery as The Mainstay Of Treatment in Retroperitoneal Sarcomas: Retrospective Data Analysis From Two Surgical Oncology But Non-Sarcoma Specialist Centres. 31st Panhellenic Surgical Conference & Surgical Forum, Athens, Greece, 21-24 of November 2018
• First-Line Folfirinox Chemotherapy in Initially Unresectable Locally Advanced Pancreatic Cancer: Retrospective Clinical Data Analysis from Two HPB Centres. 31st Panhellenic Surgical Conference & Surgical Forum, Athens, Greece, 21-24 of November 2018
• Associating Liver Partition and Portal Vein Ligation For Staged Hepatectomy Offers High Oncological Feasibility With Adequate Patient Safety: A Prospective Study At Two Centres. 31st Panhellenic Surgical Conference & Surgical Forum, Athens, Greece, 21-24 of November 2018
• Kastoris, A. C., Fragkiadakis, G., Michaelides, M., Charalambous, C., Petrou, A., & Kyprianou, T. (2017). Postoperative intensive care course of patients undergoing first and second stage of ALPPS. Abstract 0363 presented at the ESICM LIVES 2017 – 30th ESICM Annual Congress, Vienna, Austria.
Professional Memberships & Registrations
- Cyprus Medical Board – Registered Medical Practitioner (since 12 September 2013), Registration No. 5366
- Limassol Medical Association – Member
- Cyprus Medical Association – Member
- General Medical Council (GMC), United Kingdom – Full Registration (22 January 2019)
- GeSY (General Healthcare System, Cyprus) – Registered Healthcare Provider (since November 2020)