Iosif Strouthos
Deputy Director of Radiation Oncology
“Having patient’s needs as my outmost priority, my aim is treatment individualisation through proper application of all modern radiotherapy techniques always based on knowledge, research and experience.”
Dr. Iosif Strouthos was born and raised in Larnaca, Cyprus. He graduated from the American Academy Larnaca in 2003 and upon completion of his military service; he went off to study medicine in Prague, Czech Republic. After obtaining his medical degree, he temporarily returned to work in Famagusta General Hospital, where he mostly practiced in the surgical field. Following this spell, he moved to Germany for his medical specialization. He managed to become board certified radiation oncologist, while at the same time he completed his doctorate in the University of Frankfurt. During this time, he had the opportunity to work in renowned hospitals and learn from leading scientists in the field, including Professor Nikolaos Zamboglou and Professor Anca-Ligia Grosu, whilst in parallel he achieved significant academic work. Despite that, the immense need to offer back to his homeland and his desire to return to Cyprus made him join the Medical Team at the German Oncology Center. He currently lives in his hometown with his family.

Education
10/2005 – 07/2011: MD, 1st Medical School at the Charles University, Prague, Czech Republic (MUDr)
07/2015: Certificate “Application of Low level Laser Therapy/Photobiomodulation Therapy” -Thor® Company
05/2017: Board Certification Exam in Radiation Oncology (Germany)
02/2018: Doctorate at Goethe University Frankfurt, Germany - Topic: “HDR-Brachytherapy as monotherapy for patients with localized prostate cancer”
Clinical Experience / Training
08/2011 – 03/2012: Department of General Surgery, Famagusta General Hospital, Pre-registration physician
01/2013 – 12/2013: Radiation Oncology Department, Klinikum Chemnitz GmbH, Germany – Radiation Oncology Resident
01/2014 – 09/2016: Department of Interdisciplinary Oncology, Sana Klinikum Offenbach Germany – Radiation Oncology Resident
09/2016 – 08/2018: Department of Radiation Oncology, University Clinic Freiburg, Medical Center, Germany – Radiation Oncology Resident
05/2018 – 08/2018: Department of Radiation Oncology, University Clinic Freiburg, Medical Center, Germany – Radiation Oncology Consultant
08/2018 till today: Department of Radiation Oncology, German Oncology Center, Limassol, Cyprus –Radiation Oncology Consultant
Training
12/2015 Educational training “Radiotherapy for malignant disorders in childhood”, West-Germany Proton Center, Essen, Germany
04/2016 Special training course “Partial breast Irradiation with interstitial brachytherapy”, Erlangen, Germany
02/2020 ESTRO Training course on Comprehensive and Practical Brachytherapy (IAEA grant), Brussels, Belgium
Scientific Activity
Jul. 2015: Certificate „Application of Low level Laser Therapy“ – Thor® Company
Nov.2014 – Feb. 2018: Doctorate, Goethe University Frankfurt – Topic: “HDR-brachytherapy as monotherapy in patients with localized prostate cancer”
01 – 07/2016: Lecturer, Sana Klinikum Offenbach, Germany, School for Radiographers
10/2016: Lecturer, Medical Center – University of Freiburg, Medical students
02/2017: Certificate of “Good Clinical Practice” – GCP as “Primary Investigator”
Since 09/2016 Active involvement in national/European and international prospective studies
09/2016 – 07/2018: Researcher at the Study Group of the Department of Radiation Oncology, University Clinic Freiburg, Medical Center, Germany
Since 2018: Member of UroGEC group (Groupe Européen de Curiethérapie (GEC) of European Society of Radiotherapy & Oncology (ESTRO))
Membership & Distinctions
ESTRO (European Society for Radiotherapy and Oncology)
UroGEC of ESTRO (Groupe Européen de Curiethérapie (GEC) of European Society of Radiotherapy & Oncology (ESTRO))
OEK (Cyprus Oncologic Society)
DEGRO (German Society for Radiation Oncology)
Publications / Abstracts
Peer- Reviewed Publications
Metastasis-Free Survival and Patterns of Distant Metastatic Disease After Prostate-Specific Membrane Antigen Positron Emission Tomography (PSMA-PET)-Guided Salvage Radiation …, International Journal of Radiation Oncology, Biology, Physics 113 (5), 1015-1024
18F-Fluorodeoxyglucose Positron Emission Tomography of Head and Neck Cancer: Location and HPV Specific Parameters for Potential Treatment Individualization S Zschaeck, J Weingärtner, E Lombardo, S Marschner, M Hajiyianni, I Strouthos, Frontiers in oncology 12, 870319
Metastasis-free survival and patterns of distant metastatic disease after PSMA-PET-guided salvage radiotherapy in recurrent or persistent prostate cancer after prostatectomy C Zamboglou, I Strouthos, J Sahlmann, et al. International Journal of Radiation Oncology* Biology* Physics
Physical characterisation of commercial ear impression materials for use as a bolus in radiotherapy, P Doolan, G Antorkas, A Hadjipanteli, K Ferentinos, N Zamboglou, I Strouthos, Physica Medica: European Journal of Medical Physics 92, S63
Metastasis-free survival after salvage radiotherapy for post-operative prostate cancer patients in the PSMA PET/CT era–a multicenter analysis, C Zamboglou, NS Schmidt-Hegemann, L Emmett, I Strouthos, European Urology Open Science 33, S261-S262
Interstitial multicatheter HDR-brachytherapy as accelerated partial breast irradiation after second breast-conserving surgery for locally recurrent breast cancer, G Chatzikonstantinou, I Strouthos, C Scherf, J Köhn, C Solbach, C Rödel, Journal of Radiation Research 62 (3), 465-472
Intraluminal High-Dose-Rate Brachytherapy—An Alternative Organ-Preserving Approach for Primary Male Urothelial Carcinoma With Panurethral Involvement, I Strouthos, N Tselis, K Ferentinos, E Karagiannis, N Milickovic, ..., Practical Radiation Oncology 10 (1), e53-e56
Interstitial high-dose-rate brachytherapy in the primary treatment of inoperable glioblastoma multiforme, G Chatzikonstantinou, P Ulrich, E Archavlis, N Zamboglou, I Strouthos, ..., Journal of Contemporary Brachytherapy 11 (3), 215-220
Repeated SBRT for in-and out-of-field recurrences in the liver, E Gkika, I Strouthos, S Kirste, S Adebahr, M Schultheiss, D Bettinger, ..., Strahlentherapie und Onkologie 195 (3), 246-253
Outcome after PSMA PET/CT–based salvage radiotherapy in patients with biochemical recurrence after radical prostatectomy: a 2-institution retrospective analysis, NS Schmidt-Hegemann, C Stief, TH Kim, C Eze, S Kirste, I Strouthos, M Li, ..., Journal of Nuclear Medicine 60 (2), 227-233
CT-guided interstitial HDR-brachytherapy for recurrent glioblastoma multiforme: a 20-year single-institute experience, G Chatzikonstantinou, N Zamboglou, E Archavlis, I Strouthos, E Zoga, ...,Strahlentherapie und Onkologie 194 (12), 1171-1179
Inverse planning and inverse implanting for breast interstitial brachytherapy. Introducing a new anatomy specific breast interstitial template (ASBIT), E Karagiannis, A Leczynski, N Tselis, E Psanis, O Steckenreiter, I Strouthos, N Zamboglou, Radiotherapy and Oncology 128 (3), 421-427
Combined high dose rate brachytherapy and external beam radiotherapy for clinically localised prostate cancer, I Strouthos, G Chatzikonstantinou, N Zamboglou, N Milickovic, N Tselis, Radiotherapy and Oncology 128 (2), 301-307
High dose rate brachytherapy as monotherapy for localised prostate cancer, I Strouthos, N Tselis, G Chatzikonstantinou, S Butt, D Baltas, D Bon, ... ,Radiotherapy and Oncology 126 (2), 270-277
CT-Guided Interstitial HDR-Brachytherapy for Recurrent Glioblastoma Multiforme: Twenty Years Single-Institute Experience, G Chatzikonstantinou, E Archavlis, I Strouthos, E Zoga, N Milickovic, ...
Photobiomodulation therapy for the management of radiation-induced dermatitis, I Strouthos, G Chatzikonstantinou, N Tselis, D Bon, E Karagiannis, E Zoga, ... Strahlentherapie und Onkologie 193 (6), 491-498
Radiation recall dermatitis: case report I Strouthos, Reactions 1625, 86-29
Docetaxel-induced radiation recall dermatitis, I Strouthos, N Tselis, N Zamboglou Strahlentherapie und Onkologie 192 (10), 730-736, 62016
Abstracts
06/2022: Metastasis-free Survival and Distant Metastasis Patterns after PSMA-PET-guided Salvage Radiotherapy for recurrent or persistent Prostate Cancer after Prostatectomy C Zamboglou, I Strouthos, S Adebahr et al. Strahlentherapie und Onkologie 198 (SUPPL 1), S117-S117
05/2022: Hypofractionated prostate radiotherapy: alternate delineation approach vs validated trial protocol, I Strouthos, E Karagiannis, P Doolan, et al. Radiotherapy and Oncology 170, S1180-S1181
05/2022: Implementation of high-dose-rate brachytherapy as monotherapy for over-sized prostatic gland Y Roussakis, G Antorkas, A Antoniou, C Cloconi, E Karagiannis, I Strouthos, Radiotherapy and Oncology 170, S265
03/2022: Early Detection of Acute Radiation Dermatitis (ARD) Using In Vivo Optical Coherence Tomography (OCT) Images, C Photiou, I Strouthos, C Cloconi, Optical Coherence Tomography, CM2E. 4
03/2022: In vivo early detection of acute radiation dermatitis using optical coherence tomography (OCT) images, C Photiou, I Strouthos, C Cloconi, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, 1194808
10/2021: Automatic segmentation of prostate on TRUS images using convolutional neural networks, F Paskali, T Fechter, C Zambgolou, I Strouthos, L Georgiou, D Baltas, Physica Medica: European Journal of Medical Physics 92, S198
05/2021: A comparison of three commercial AI contouring solutions, P Doolan, S Charalambous, Y Roussakis, A Leczynski, K Ferentinos, I Strouthos, E Karagiannis, Radiotherapy and Oncology 161, S1221-S1222
05/21: Interstitial multicatheter High-Dose-Rate Brachytherapy as adjuvant accelerated Partial Breast Irradiation after repeated Breast-conserving Therapy in Patients with ipsilateral …,G Chatzikonstantinou, I Strouthos, C Scherf, J Koehn, C Solbach, Strahlentherapie und Onkologie 197 (SUPPL 1), S54-S55
05/2021: Metastasis-free survival after salvage radiotherapy in post-operative prostate cancer patients in the PSMA PET/-CT era-a tri-institutional, retrospective analysis, C Zamboglou, I Strouthos, AL Grosu, S Kirste, K Ferentinos, J Ruf, ..., STRAHLENTHERAPIE UND ONKOLOGIE 197 (SUPPL 1), S13-S14
05/2021: HEPANOVA: a phase 2 trial of tumor treating fields concomitant with sorafenib for advanced hepatocellular carcinoma, AL Grosu, I Strouthos, E Gkika, T Brunner, U Weinberg, A Kinzel, STRAHLENTHERAPIE UND ONKOLOGIE 195, S104-S104
06/2018: The Role of local curative Therapy in oligometastatic NSCLC, E Gkika, D Schiebahn, A Bunea, H Bunea, T Schimek-Jasch, S Adebahr, I Strouthos ...,STRAHLENTHERAPIE UND ONKOLOGIE 194, S80-S80
06/2018: The Role of FDG PET/CT in SBRT of primary Tumors in the Upper Abdomen, E Gkika, N Bartl, I Strouthos, S Adebahr, S Kirste, I Popp, H Schaefer, ..., STRAHLENTHERAPIE UND ONKOLOGIE 194, S88-S89
06/2018: The prognostic Significance of the Neutrophil/Lymphocyte Ratio in the SBRT of cholangiocellular Carcinomas, E Gkika, N Bartl, I Strouthos, S Adebahr, I Popp, H Schaefer, AL Grosu, ..., STRAHLENTHERAPIE UND ONKOLOGIE 194, S104-S105
06/2018: High dose rate brachytherapy boost plus external beam radiotherapy for high risk localized prostate cancer, I Strouthos, G Chatzikonstantinou, N Milickovic, S Papaioannou, ... STRAHLENTHERAPIE UND ONKOLOGIE 194, S20-S20
06/2018: Evaluation of simultaneously integrated Protection (SIP) in the Upper Abdomen SBRT, E Gkika, I Strouthos, N Bartl, I Popp, S Adebahr, S Kirste, H Schaefer, .., STRAHLENTHERAPIE UND ONKOLOGIE 194, S105-S105
05/2018: Interobserver and interfraction variability using free-breathing cbCT for SBRT of the upper abdomen, L Nicosia, T Brunner, I Popp, E Gkika, F Capilli, HC Rischke, I Strouthos ..., Radiotherapy and Oncology 127, S790-S791
05/2018: Safety of repeated stereotactic body radiotherapy (SBRT) for recurrent liver malignancies, E Gkika, I Strouthos, S Adebahr, S Kirste, D Bettinger, R Fritsch, V Brass, ..., Radiotherapy and Oncology 127, S778-S779
05/2018: High dose rate brachytherapy plus external beam radiotherapy for localized prostate cancer, I Strouthos, G Chatzikonstantinou, N Tselis, N Milickovic, S Papaioannou, ..., Radiotherapy and Oncology 127, S427
06/2017: Photobiomodulation therapy for the management of radiation-induced dermatitis: a single-institution experience during adjuvant radiotherapy in breast cancer patients after …, I Strouthos, G Chatzikonstantinou, E Karagiannis, E Zoga, K Ferentinos, .., STRAHLENTHERAPIE UND ONKOLOGIE 193, S168-S169
06/2017: High dose rate brachytherapy as monotherapy for organ confined prostate cancer: a three-implant-three-fraction approach in 450 consecutive patients, I Strouthos, N Tselis, G Chatzikonstantinou, S Butt, D Baltas, N Milickovic, ... STRAHLENTHERAPIE UND ONKOLOGIE 193, S135-S135
06/2017: Inverse planning for breast interstitial brachytherapy. Introducing a new Anatomy Specific Breast Interstitial Template (ASBIT), E Karagiannis, A Leczynski, N Tselis, E Psanis, O Steckenreiter, I Strouthos ... STRAHLENTHERAPIE UND ONKOLOGIE 193, S30-S31
Invited Articles / reviews
Narrative Review of High-Dose-Rate Interstitial Brachytherapy in Primary or Secondary Liver Tumors, E Karagiannis, I Strouthos, A Leczynski, N Zamboglou, K Ferentinos, Frontiers in Oncology
High‐dose‐rate brachytherapy for prostate cancer: Rationale, current applications, and clinical outcome, I Strouthos, E Karagiannis, N Zamboglou, K Ferentinos, Cancer Reports 5 (1), e1450
Computed tomography guided interstitial percutaneous high-dose-rate brachytherapy in the management of lung malignancies. A review of the literature, K Ferentinos, E Karagiannis, I Strouthos, A Vrachimis, PJ Doolan, Brachytherapy 20 (4), 892-899
High-dose-rate brachytherapy as salvage modality for locally recurrent prostate cancer after definitive radiotherapy G Chatzikonstantinou, N Zamboglou, C Rödel, E Zoga, I Strouthos, ..., Strahlentherapie und Onkologie 193 (9), 683-691
